Balsa is a small and light email client written by the Gnome people. As such it has tight integration with Gnome however works quite well with other desktops or window managers.
Install the Official Repositories.package, available from the
Balsa launches with the normal email client setup wizard that takes you through most setup. In addition there is a preferences item on the edit menu. Configuration files can be found in ~/.balsa.
One issue to which I found no good solution (unless you are running gnome) is configuring the browser to use when you click on a link in an email. I found no solution that works with my window manager: fluxbox.
The following is a dreadful hack but works:
1) click on a link in an email and note which browser it is trying to load - in my case /usr/lib/firefox/firefox.
2) Check how much of that path exists and create what is missing. I had to create /usr/lib/firefox
3) Make a soft link to your preferred browser - in my case /usr/bin/chromium
ln -s /usr/bin/chromium /usr/lib/firefox/firefox