Bottles is a Wine prefix manager written in Python using the GTK framework. It can be used to create and manage Wine prefixes as well as automatically handling the installation of various Wine runners, Windows dependencies and installation of some Windows applications. It can also be used to override Windows DLL files inside a prefix and manage environment variables for Wine sessions.
It can be used to run Native Windows applications and games with, in most cases, near native performance and in its officially supported mode also supports application sandboxing.
Install Bottles from Flatpak using the following command
$ flatpak install bottles
Alternatively, Bottles is also available as an AUR package as AUR.
Bottles has a thorough guide covering its usage at Bottles User Documentation